Abnormalno ljuspanje ćelija u površinskim podslojevima kože, abnormalno vezivanje ćelija unutar folikula dlake ("hiperkeratinizacija"), i nagomilavanje vode unutar kože (koje izaziva nadimanje tkiva kože i pritisak na kanale sve do njihovog zatvaranja) su pojave predložene kao važni delujući mehanizmi.Ako je bubuljica velika i/ili ne reagi
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